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Showing posts with label Against. Show all posts
Showing posts with label Against. Show all posts

Thursday, January 3, 2013

In The Battle Against Heart Disease, Stroke, Unhealthy Behaviors Could Slow Progress

Main Category: Obesity / Weight Loss / Fitness
Also Included In: Stroke;  Heart Disease;  Public Health
Article Date: 17 Dec 2012 - 0:00 PST Current ratings for:
In The Battle Against Heart Disease, Stroke, Unhealthy Behaviors Could Slow Progress
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Poor eating and exercise habits could be the game-changer in the fight against heart disease and stroke deaths, according to the American Heart Association's "Heart Disease and Stroke Statistical Update 2013," published in the American Heart Association journal, Circulation.

"Americans need to move a lot more, eat healthier and less, and manage risk factors as soon as they develop," said Alan S. Go, M.D., chairman of the report's writing committee and chief of the Cardiovascular and Metabolic Conditions Section of the Kaiser Permanente Northern California Division of Research in Oakland. "If not, we'll quickly lose the momentum we've gained in reducing heart attack and stroke rates and improving survival over the last few decades."

Between 1999 and 2009, the rate of deaths from cardiovascular disease (CVD) fell 32.7 percent, but still accounted for nearly one in three deaths in the nation. That's 2,150 people dying from CVD each day - about one death every 40 seconds.

In 2010, the American Heart Association set a goal to improve cardiovascular health of all Americans by 20 percent and reduce heart disease and stroke deaths 20 percent by 2020.

However, according to projections in the 2013 report, heart health may only improve by 6 percent if current trends continue. The biggest barriers to success are projected increases in obesity and diabetes, and only modest improvements in diet and physical activity. On a positive note, smoking, high cholesterol and high blood pressure rates are projected to decline.

Among heart disease and stroke risk factors, the most recent data shows: More adults age 20 and over are obese (34.6 percent) than normal or underweight (31.8 percent); 68.2 percent are overweight or obese. Among children ages 2-19, 31.8 percent are overweight or obese. Thirty-two percent of adults report no aerobic activity; 17.7 percent of girls and 10 percent of boys, grades 9-12, report fewer than an hour of aerobic activity in the past week. 13.8 percent of adults have total cholesterol of 240 mg/dL or higher. Thirty-three percent of adults have high blood pressure; African-Americans have among the highest prevalence of high blood pressure (44 percent) worldwide. 8.3 percent of adults have diagnosed diabetes, and 8.2 percent have undiagnosed diabetes; 38.2 percent have prediabetes. Despite four decades of improvement, 21.3 percent of men and 16.7 percent of women age 18 and over still smoke cigarettes; 18.1 percent of students in grades 9-12 report cigarette smoking.

"As the leader in the fight against heart disease and stroke, we are taking a more aggressive and innovative approach, including taking some pages from the playbooks of the public health sector," said Donna Arnett, Ph.D., president of the American Heart Association and chairperson of the Department of Epidemiology at the University of Alabama at Birmingham School of Public Health. "We're focusing on population-based ways to improve health factors for all Americans."

Some of these include: Working with healthcare systems to support and reward providers who help patients improve their health behaviors and manage their health risk factors. Working with insurers to cover preventive health services and reward positive health behaviors and medication adherence. Working with the education community to make changes in schools that support healthy diets and physical activity for children. Building comprehensive worksite wellness programs. Building healthier communities with improved access to healthier foods and green space for physical activity. The association has a wide range of programs and policy initiatives aimed at improving cardiovascular health through risk factor prevention and health care quality, Arnett said. Information on improving your heart health can be found at http://www.MyHeartMyLife.org.

"In this race against time, it will take nationwide efforts driven by communities and systems - a patient-by-patient approach alone won't do it," Arnett said. "But we're optimistic that if we increase our efforts for improvements in prevention and reductions in risk factors, we can be successful - we can save lives."

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our obesity / weight loss / fitness section for the latest news on this subject. Additional authors and disclosures are on the manuscript.
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Monday, July 23, 2012

'Good' Cholesterol, May Not Protect Against Heart Disease

Main Category: Heart Disease
Also Included In: Cholesterol
Article Date: 09 May 2012 - 1:00 PDT Current ratings for:
''Good' Cholesterol, May Not Protect Against Heart Disease'
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A new study by Harvard School of Public Health (HSPH) researchers has found that a subclass of high-density lipoprotein (HDL) cholesterol, the so-called "good" cholesterol, may not protect against coronary heart disease (CHD) and in fact may be harmful.

This is the first study to show that a small protein, apolipoprotein C-III (apoC-III), that sometimes resides on the surface of HDL cholesterol may increase the risk of heart disease and that HDL cholesterol without this protein may be especially heart protective.

The study was published online in the Journal of the American Heart Association.

"This finding, if confirmed in ongoing studies, could lead to better evaluation of risk of heart disease in individuals and to more precise targeting of treatments to raise the protective HDL or lower the unfavorable HDL with apoC-III," said Frank Sacks, professor of cardiovascular disease prevention at HSPH and senior author of the study.

A high level of HDL cholesterol is strongly predictive of a low incidence of coronary heart disease (CHD). But trials of drugs that increase HDL cholesterol have not consistently shown decreases in CHD, leading to the hypothesis that HDL cholesterol may contain both protective and non-protective components.

ApoC-III, a proinflammatory protein, resides on the surface of some lipoproteins - both HDL and low-density lipoproteins, or LDL ("bad") cholesterol. The researchers, led by Sacks and Majken Jensen, research associate in the Department of Nutrition at HSPH, examined whether the existence or absence of apoC-III on HDL cholesterol affected the "good" cholesterol's heart-protective qualities, and whether its existence could differentiate HDL cholesterol into two subclasses - those which protect against the risk of future heart disease and those which do not.

Blood samples collected in 1989 and 1990 from 32,826 women in the Brigham and Women's Hospital-based Nurses' Health Study were examined, along with blood samples collected from 1993 to 1995 from 18,225 men in the Health Professionals Follow-up Study. During 10 to 14 years of follow-up, 634 cases of coronary heart disease were documented and matched with controls for age, smoking, and date of blood drawing.

The researchers compared plasma concentrations of total HDL, HDL that has apoC-III, and HDL without apoC-III as predictors of the risk of CHD.

After adjusting for age, smoking status and other dietary and lifestyle cardiovascular risk factors, the researchers found that two different subclasses of HDL have opposite associations with the risk of CHD in apparently healthy men and women. The major HDL type, which lacks apoC-III, had the expected heart-protective association with CHD. But the small fraction (13%) of HDL cholesterol that has apoC-III present on its surface was paradoxically associated with a higher, not lower, risk of future CHD. Those men and women who had HDL apoC-III in the highest 20% of the population had a 60% increased risk of CHD.

The results suggest that measuring HDL apoC-III and HDL without apoC-III rather than the simpler measure of total HDL may be a better gauge of heart disease risk (or of HDL's protective capacity). "Reduction in HDL-apoC-III by diet or drug treatments may become an indicator of efficacy," said Jensen.

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our heart disease section for the latest news on this subject. The study was supported by The National Institutes of Health and the Villum Kann Rasmussen Foundation (Denmark).
"Apolipoprotein C-III as a Potential Modulator of the Association Between HDL-Cholesterol and Incident Coronary Heart Disease," Majken K. Jensen, Eric B. Rimm, Jeremy D. Furtado, Frank M. Sacks, Journal of the American Heart Association, April 2012.
Harvard School of Public Health Please use one of the following formats to cite this article in your essay, paper or report:

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Harvard School of Public Health. "'Good' Cholesterol, May Not Protect Against Heart Disease." Medical News Today. MediLexicon, Intl., 9 May. 2012. Web.
7 Jun. 2012. APA

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''Good' Cholesterol, May Not Protect Against Heart Disease'

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Saturday, July 7, 2012

Laws In Brazil That Protect Against "Big Food" And "Big Snack"

Main Category: Nutrition / Diet
Also Included In: Public Health;  Obesity / Weight Loss / Fitness
Article Date: 05 Jul 2012 - 1:00 PDT Current ratings for:
Laws In Brazil That Protect Against "Big Food" And "Big Snack"
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Under pressure from civil society organizations, the Brazilian government has introduced legislation to protect and improve its traditional food system, standing in contrast to the governments of many industrialized countries that have partly surrendered their prime duty to protect public health to transnational food companies, argue nutrition and public health experts writing in this week's PLoS Medicine.

Carlos Monteiro and Geoffrey Cannon, from the Center for Epidemiological Studies in Health and Nutrition of the University of São Paulo, explain that, in Brazil, traditional long-established food systems and dietary patterns are being displaced by ultra-processed products made by transnational food corporations ("Big Food" and "Big Snack") contributing to increases in the incidence of obesity and of major chronic diseases, and adversely affecting public health and public goods by undermining culture, meals, the family, community life, local economies, and national identity.

The authors argue: "The use of law to protect and improve food systems and supplies, and thus public health, may be difficult in parts of the world where governments have already ceded the responsibility of governance to transnational and other corporations. However, in Brazil protection of public health still remains a prime duty of government ."

The authors explain that by law, all Brazilian children attending state schools are entitled to one daily meal at school, at least 70% of the food supplied to schools must be fresh or minimally processed, and a minimum of 30% of this food must be sourced from local family farmers. They say that such measures help to check the penetration of transnational corporations into Brazil.

Although the penetration of such corporations into Brazil has been rapid, the tradition of shared and family meals remains strong and is likely to provide protection to national and regional food systems.

The authors say: "Notwithstanding intense pressures, which include ubiquitous television and internet propaganda designed to turn eating and drinking into constant individual snacking, food and drink consumption is not yet dislocated and isolated from family and social life in Brazil."

The authors argue that Brazil's experiences in resisting "Big Food" and "Big Snack" can help other countries. They say: "the Brazilian experience provides a basis for the design of rational, comprehensive, and effective public health policies and actions designed to protect and promote nutrition in all its senses."

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our nutrition / diet section for the latest news on this subject. This article is one in a PLoS Medicine series on Big Food that examines the activities and influence of the food and beverage industry in the health arena. The series runs for three weeks beginning 19 June 2012 and all articles will be collected at http://www.ploscollections.org/bigfood.
Funding: No specific funding was received for writing this article.
Competing Interests: Since 1993 GC has worked for the World Cancer Research Fund International and the American Institute for Cancer Research (both not-for-profit organisations). He is an honorary Council member of the World Public Health Nutrition Association, its Publications Secretary, and editor of its journal World Nutrition. GC was an advisor to the Brazilian federal government in the period 2000 - when he worked within its Ministry of Health, and also occasionally for UN agencies including WHO. GC has occasionally advised the food and beverage industry, but not since 2007 when he advised PepsiCo on the possibility of ethically based products using the products of Brazilian tropical fruits. CAM has acted as advisor to the Brazilian Ministry of Health and also for WHO.
Citation: Monteiro CA, Cannon G (2012) The Impact of Transnational ''Big Food'' Companies on the South: A View from Brazil. PLoS Med 9(7): e1001252.doi:10.1371/journal.pmed.1001252
http://www.plosmedicine.org/article/info%3Adoi%2F10.1371%2Fjournal.pmed.1001252
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Nicotinamide Riboside In Milk May Protect Against Obesity

Main Category: Obesity / Weight Loss / Fitness
Also Included In: Nutrition / Diet
Article Date: 07 Jun 2012 - 1:00 PDT Current ratings for:
'Nicotinamide Riboside In Milk May Protect Against Obesity'
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A natural ingredient found in milk can protect against obesity even as mice continue to enjoy diets that are high in fat. The researchers who report their findings in the June Cell Metabolism, a Cell Press publication, liken this milk ingredient to a new kind of vitamin.

"This is present in what we've all been eating since day one," says Johan Auwerx of Ecole Polytechnique Fédérale de Lausanne.

The researchers identified this ingredient, known as nicotinamide riboside, as they were searching for alternative ways to boost the well-known gene SIRT1, which comes with benefits for both metabolism and longevity. One way to do that is to target SIRT1 directly, as the red wine ingredient resveratrol appears to do, at least at some doses.

Auwerx's team suspected there might be a simpler way to go about it, by boosting levels of one of SIRT1's molecular sidekicks, the cofactor NAD+.

This milk ingredient does just that in a rather appealing way. Not only is it a natural product, but it also gets trapped within cells, where it can do its magic.

Mice that take nicotinamide riboside in fairly high doses along with their high-fat meals burn more fat and are protected from obesity. They also become better runners thanks to muscles that have greater endurance.

The benefits they observe in mice wouldn't be easy to get from drinking milk alone, Auwerx says. It may be more likely that the compound would serve as a new kind of metabolism-boosting supplement. Tests done in people are now needed to help sort out those details.

On the other hand, he says, this milk substance ultimately offers the same benefits attributed to resveratrol, but in a different way. It's possible that many small effects of ingredients found in our diets could add up to slimmer waistlines - perhaps longer lives, too.

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
Visit our obesity / weight loss / fitness section for the latest news on this subject. Canto et al.: "The NAD+ precursor nicotinamide riboside enhances oxidative metabolism and protects against high-fat diet induced obesity."
Cell Press Please use one of the following formats to cite this article in your essay, paper or report:

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'Nicotinamide Riboside In Milk May Protect Against Obesity'

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View the original article here